Funded M.Sc. by Research position
A 12-month M.Sc. by Research position is available in Prof. Ciaran Morrison’s lab to study the involvement of centrosomes in the cellular response to DNA damage. The position carries a stipend of €16,000 + fees and is available from 1.10.2013. The research will involve molecular and cell biology analysis of DNA damage reponses in cultured cells.
Interested candidates should have a First or Upper Second class degree in a related area and previous laboratory experience. Please send CVs to firstname.lastname@example.org for further information and discussion. The position will remain open until filled, which should be by 1.10.2013.
For details of our work, please see http://www.chromosome.ie/researchers/morrison/
Funded M.Sc. by Research position
A 12-month M.Sc. by Research position is available in Prof. Brian McStay’s lab to study the genomic architecture of human nucleolar organizer regions. The position carries a stipend of €16,000 + fees and is available from 1.10.2013. The research will involve development of genome editing tools.
Interested candidates should have a First or Upper Second class degree in a related area and previous laboratory experience. Please send CVs to email@example.com for further information and discussion. The position will remain open until filled, which should be by 1.10.2013.
For details of our work, please see http://www.chromosome.ie/researchers/mcstay/
Funded PhD Scholarship
Project Title: Regulation of Centromere Assembly in Meiosis.
Supervisor: Dr. Elaine Dunleavy
Duration: Funded for 4 years (Structured PhD), full-time.
Project description: My laboratory studies fundamental cellular processes required for the correct transmission of genetic material during cell division cycles. Specifically, my research focuses on the regulation of centromeres, key regions of eukaryotic chromosomes where kinetochores assemble to ensure proper chromosome segregation during mitosis and meiosis. Surprisingly, centromere identity is not determined by DNA sequence, rather it is specified epigenetically by the presence of the centromere-specific histone variant CENP-A. During mitosis, errors in CENP-A assembly result in genome instability and aneuploidy, both hallmarks of cancer. Yet the roles and regulation of CENP-A assembly in meiosis, the specialised cell division cycle that results in the production of haploid gametes, are at present largely unknown.
In my laboratory, I use the fruit fly Drosophila melanogaster as a model developmental system to investigate the function and regulation of CENP-A incorporation at centromeres during meiosis and gametogenesis. Using complementary biochemical and genetic approaches, this PhD project aims to identify novel factors, and elucidate mechanisms, required for CENP-A incorporation in sperm and eggs. The successful candidate should have strong interest in biochemistry, genetics, developmental, cell and molecular biology. Methodologies applied will include fly genetics, protein purifications, mass spectrometry, and fluorescence and live imaging using state-of-the-art microscopy techniques.
Stipend: 16,000 Euro per annum & fees for 4 years.
Entry Requirements: Bachelor of Science in Biochemistry, Genetics, Microbiology or a related discipline.
Expected start date: September 2013.
How to apply: To apply please send your CV (including the names of two referees) and a one-page statement of why you wish to pursue a PhD in chromosome biology that includes a brief description of any previous research experience to Dr. Elaine Dunleavy via email to firstname.lastname@example.org
Closing date for applications: July 31st 2013
Further information is available at http://www.chromosome.ie/researchers/dunleavy/
For informal discussion, contact Dr. Elaine Dunleavy (Elaine.email@example.com), Tel: +353 91 494046
Open postdoctoral positions are advertised on the NUI Galway human resources website and in the international scientific media.
Candidates interested in pursuing fellowship applications to national (IRCSET, HRB, Breast Cancer Campaign, Wellcome Trust etc.) or international (EMBO, HFSP, Marie Curie, etc.) agencies should contact potential supervisors directly.
Undergraduate summer studentships
Groups in the Centre occasionally take on undergraduate students each year for 10-12 weeks over the summer for research experience. These students may be supported by grants from funding bodies such as the Biochemical Society or Health Research Board, or by the group directly.
Support is usually targeted at students about to enter their final year of study in biochemistry, and international candidates are encouraged to apply. Interested candidates should contact potential supervisors to discuss possible options.